How to implement digital signature in pdf file using asp.net

using (MemoryStream ms = new MemoryStream())
{
   Document document = new Document(PageSize.A4, 25, 25, 30, 30);
   PdfWriter writer = PdfWriter.GetInstance(document, ms);
   document.Open();
   document.Add(new Paragraph("Hello World"));
   document.Close();
   writer.Close();
   Response.ContentType = "pdf/application";
   Response.AddHeader("content-disposition", 
   "attachment;filename=First PDF document.pdf");
   Response.OutputStream.Write(ms.GetBuffer(), 0, ms.GetBuffer().Length);
}