Private Sub DataGridView1_CurrentCellDirtyStateChanged(ByVal sender As Object, ByVal e As System.EventArgs) Handles DataGridView1.CurrentCellDirtyStateChanged

        Dim dgCheckBoxCell As DataGridViewCheckBoxCell

        Try
            'Checking whether the Datagridview Checkbox column is the first column
            If DataGridView1.CurrentCellAddress.X = 0 Then
                dgCheckBoxCell = DataGridView1.CurrentRow.Cells(0)

                If (DataGridView1.IsCurrentCellDirty) Then 'Checking for dirty cell
                    DataGridView1.CommitEdit(DataGridViewDataErrorContexts.Commit) 'If it is dirty, making them to commit

                    If (dgCheckBoxCell.Value) Then
                        'Enabling the selected row editable for sample.

                        DataGridView1.CurrentRow.Cells("EmpID").ReadOnly = False
                        DataGridView1.CurrentRow.Cells("Designtn").ReadOnly = False
                        DataGridView1.CurrentRow.Cells("Location").ReadOnly = False
                        DataGridView1.CurrentRow.Cells("Experience").ReadOnly = False

                    Else
                        'Disabling the selected row for editing.

                        DataGridView1.CurrentRow.Cells("EmpID").ReadOnly = True
                        DataGridView1.CurrentRow.Cells("Designtn").ReadOnly = True
                        DataGridView1.CurrentRow.Cells("Location").ReadOnly = True
                        DataGridView1.CurrentRow.Cells("Experience").ReadOnly = True

                    End If
                End If
            End If

        Catch ex As Exception
        End Try
    End Sub