Windows application on IIS ? what you mean by that ? Windows application does not run browser, You may call any installed exe from browser using ActiveX component but it is consider as security threat.
ClickOnceDeployment is the way that will install a windows application on client machine through browser but it is bit different concept
Till now the answer of your question is No.
Editor, DotNetSpider MVM
Microsoft MVP 2014 [ASP.NET/IIS]