Private Sub Page_Load(ByVal sender As System.Object, ByVal e As
System.EventArgs) Handles MyBase.Load

If Not Page.IsPostBack Then
Dim MyList As New ArrayList
Dim i As Int32

For i = 0 To 3
MyList.Add(i)
Next
DataGrid1.DataSource = MyList
DataGrid1.DataBind()
Else
Dim i As Int32
For i = 0 To DataGrid1.Items.Count - 1
Dim ck As CheckBox
ck = DataGrid1.Items(i).Cells(0).FindControl("CheckBox1 ")
Response.Write(ck.Checked & "<br>")
'do databse code here
Next
End If
End Sub

 private void dataGridView1_EditingControlShowing(object sender, DataGridViewEditingControlShowingEventArgs e)
        {
            CheckBox ck = e.Control as CheckBox;
            if (ck != null)
            {
                ck.CheckedChanged += new EventHandler(ck_CheckedChanged);
            }
        }



        void ck_CheckedChanged(object sender, EventArgs e)
        {
            throw new NotImplementedException();
        }